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. 2011 Mar 4;183(12):1715–1722. doi: 10.1164/rccm.201101-0055OC

TABLE 3.

MODEL PREDICTION C STATISTIC (AKIN TO AREA UNDER THE RECEIVER–OPERATING CHARACTERISTIC CURVE) AND INDIVIDUAL VARIABLES FOR DAYS 1–28 MODELS FOR THE DEVELOPMENT COHORT*

Day 1
Day 3
Day 7
Variable C Statistic Variable C Statistic Variable C Statistic
Gestational age 0.750 Gestational age 0.745 Respiratory support 0.771
Birth weight 0.772 Respiratory support 0.787 Gestational age 0.806
FiO2 0.784 Birth weight 0.798 Birth weight 0.814
Respiratory support 0.790 FiO2 0.805 FiO2 0.817
Race and ethnicity 0.791 Male sex 0.807 Race and ethnicity 0.817
Male sex 0.793 Race and ethnicity 0.807 Male sex 0.818
Day 14
Day 21
Day 28
Variable
C Statistic
Variable
C Statistic
Variable
C Statistic
Respiratory support 0.795 Respiratory support 0.802 Respiratory support 0.823
Birth weight 0.819 FiO2 0.831 FiO2 0.852
Gestational age 0.825 Gestational age 0.833 Birth weight 0.851
FiO2 0.826 Birth weight 0.835 Race and ethnicity 0.853
Race and ethnicity 0.826 Race and ethnicity 0.835 Gestational age 0.853
Male sex 0.827 Male sex 0.836 Male sex 0.854
*

For example, on Day 7, respiratory support provides 77.1% of the predictive ability of the C statistic, with a small incremental increase in the C statistic with additional variables to a final model C statistic of 81.8%.