Table 4. Results of parameter scan for stochastic model under normal conditions.

Parameter	NatP	Total MisP	Free pool of Hsp70	Free pool of Hsp90
kmisfold	↓ 0.114	↑ 0.864	↓ 0.172	↓0.173
kbinMisPProt	↓ 0.063	↓0.173	↑ 0.037	↑ 0.036
krefold	↑ 0.057	↓ 0.444	↑ 0.096	↑ 0.096
kbasalsynHsp70	↓ 0.006	↑0.027	↑ 0.157	↔ 0.000
kbasalsynHsp90	↓ 0.006	↑0.027	↑ 0.014	↑ 0.131
kbinHsp70Prot	↓ 0.006	↑ 0.032	↓ 0.164	↓ 0.028
kbinHsp90Prot	↓ 0.006	↑ 0.008	↓ 0.014	↓ 0.135
kgenROS	↓ 0.108	↑ 0.752	↓ 0.164	↓ 0.169
kremROS	↑ 0.063	↓ 0.492	↑ 0.107	↑ 0.107

Each parameter was increased to double its initial value and 20 repeat simulations were carried out over a 10 hour period. The results show the effect on the mean values of NatP, MisP (including MisP bound to Hsps and the proteasome), free pools of Hsp70 and free pools of Hsp90. The arrows show the direction of change, the numbers indicate the proportional change in the species value when the parameter value is doubled (), where the denominator is equal to one, if the parameter value k is double). Effects which are greater than 10% are indicated in boldface.