Native protein |
NatP |
CHEBI:36080 |
17600 |
Misfolded protein |
MisP |
CHEBI:36080 |
0 |
Aggregated protein |
AggP |
CHEBI:36080 |
0 |
MisP bound to Hsp70 |
Hsp70_MisP |
IPR001023, CHEBI:36080 |
470 |
MisP bound to Hsp90 |
Hsp90_MisP |
IPR001404, CHEBI:36080 |
410 |
Hsp70 |
Hsp70 |
IPR001023 |
1400 |
Hsp90 |
Hsp90 |
IPR001404 |
1850 |
Damaged Hsp70 |
Hsp70_dam |
IPR001023 |
0 |
Damaged Hsp90 |
Hsp90_dam |
IPR001404 |
0 |
Hsp70 bound to proteasome |
Hsp70_Proteasome |
IPR001023, GO:0000502 |
0 |
Hsp90 bound to proteasome |
Hsp90_Proteasome |
IPR001404 GO:0000502 |
0 |
Hsf1 |
Hsf1 |
Q00613 |
5 |
Hsf1 bound to Hsp90 |
Hsf1_Hsp90 |
Q00613, IPR001404 |
95 |
Hsf1 dimers |
Hsf1_Hsf1 |
Q00613 |
0 |
Hsf1 trimers |
Hsf1_Hsf1_Hsf1 |
Q00613 |
0 |
Phosphorylated Hsf1 trimers |
Hsf1_Hsf1_Hsf1_P |
Q00613 |
0 |
Hsp70 heat shock element |
HSEHsp70 |
SBO:0000369 |
2 |
Hsp90 heat shock element |
HSEHsp90 |
SBO:0000369 |
2 |
Phosphorylated Hsf1 bound to HSEHsp70 |
HSEHsp70_Hsf1_Hsf1_Hsf1_P |
SBO:0000369, Q00613
|
0 |
Unphosphorylated Hsf1 bound to HSEHsp70 |
HSEHsp70_Hsf1_Hsf1_Hsf1 |
SBO:0000369, Q00613
|
0 |
Phosphorylated Hsf1 bound to HSEHsp90 |
HSEHsp90_Hsf1_Hsf1_Hsf1_P |
SBO:0000369, Q00613
|
0 |
Unphosphorylated Hsf1 bound to HSEHsp90 |
HSEHsp90_Hsf1_Hsf1_Hsf1 |
SBO:0000369, Q00613
|
0 |
Hsp70 client proteins |
Hsp70Client |
CHEBI:36080 |
490 |
Hsp90 client proteins |
Hsp90Client |
CHEBI:36080 |
590 |
Hsp70 bound to clients |
Hsp70_Hsp70Client |
IPR001023, CHEBI:36080 |
10 |
Hsp90 bound to clients |
Hsp90_Hsp90Client |
IPR001404, CHEBI:36080 |
10 |
Akt (protein kinase B) |
Akt |
P31749 |
340 |
Akt bound to Hsp90 |
Akt_Hsp90 |
P31749, IPR001404 |
30 |
Carboxy terminus of Hsp70-interacting protein |
CHIP |
Q9UNE7 |
255 |
Akt bound to CHIP/Hsp90 complex |
Akt_CHIP_Hsp90 |
P31749, Q9UNE7, IPR001404 |
80 |
Akt bound to proteasome |
Akt_Proteasome |
P31749, GO:0000502 |
0 |
Proteasome |
Proteasome |
GO:0000502 |
500 |
MisP bound to proteasome |
MisP_Proteasome |
CHEBI:36080,GO:0000502 |
0 |
Aggregated protein bound to proteasome |
AggP_Proteasome |
CHEBI:36080, GO:0000502 |
0 |
Sequestered aggregated protein |
SeqAggP |
CHEBI:36080 |
0 |
Phosphatase Mkp1 (DUSP1) |
Mkp1 |
P28562 |
0 |
Phosphorylated Mkp1 |
Mkp1_P |
P28562 |
100 |
Mkp1 bound to proteasome |
Mkp1_Proteasome |
P28562, GO:0000502 |
0 |
Phosphatase for Hsf1 |
Ppx |
GO:0008287 |
0 |
PPX bound to Hsp70 |
Hsp70_Ppx |
IPR001023, GO:0008287 |
100 |
JNK (MAPK8) |
Jnk |
P45983 |
100 |
Phosphorylated JNK |
Jnk_P |
P45983 |
0 |
p38MAPK (MAPK14) |
p38 |
Q16539 |
100 |
Phosphorylated p38MAPK |
p38_P |
Q16539 |
0 |
Protein kinase C |
Pkc |
IPR015745 |
100 |
Reactive oxygen species |
ROS |
CHEBI:26523 |
10 |
Adenosine triphosphate |
ATP |
CHEBI:15422 |
10000 |
Adenosine diphosphate |
ADP |
CHEBI:16761 |
1000 |