Fig. 2.

Effect of rHDL on the lipoprotein distribution of human apoAI and phospholipids at 1 h after injection in E3L and E3L.CETP mice. E3L (A, C) and E3L.CETP (B, D) mice were fed a Western-type diet for three weeks. Subsequently, they received a single intravenous injection of rHDL (250 mg/kg in 250 µl PBS) or vehicle. After 1 h, blood was drawn, and plasma was pooled per group (n = 8-10). Pooled plasma was fractionated using FPLC on a Superose 6 column, and the individual fractions were assayed for human apoAI (A, B) and phospholipids (C, D).