TABLE 3.

AID-catalyzed deamination efficiencies for clones with one mutation compared with clones with multiple mutations

* Deaminations in AAC and GAC motifs were counted for the middle and the right cassettes (Fig. 1b).

** In Fig. 1d, a single deamination at the AAC motif in the right cassette cannot be detected, because it does not generate a stop codon; therefore, single deaminations in the GTC motif (which do generate stop codons) were compared with deamination in the AAC motif in the left cassette (which do generate stop codons).