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G1 or G2 effectively block infection in a mouse model of corneal keratitis. 100 μl of G1, G2, or Cp (control) peptide at 0.5 mm concentration was poured into the mouse cornea as a prophylactic “eye drop” followed by an infection with HSV-1(KOS) at 106 pfu. At 4 or 7 days post-infection, immunohistochemistry was performed using anti-HSV-1 gD polyclonal antibody. Staining for HSV-1 is shown in brown.
