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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: Ann N Y Acad Sci. 2009 Sep;1171(Suppl 1):E75–E85. doi: 10.1111/j.1749-6632.2009.05054.x

Figure 1.

Figure 1

Effects of ActD on the replication of MP-12 and MP-12 lacking the NSs gene. The Fig is adapted from Ikegami et al.[26] (A) Schematic representations of the S segments of MP-12 and rMP12-rLuc. (B) Type I IFN-deficient VeroE6 cells were mock-treated or independently infected with MP-12 and rMP12-rLuc at an moi of 3, immediately treated with ActD (5 μg/ml) or left untreated, and culture fluids were harvested at 16 h.p.i. Virus titers of MP-12 and rMP12-rLuc were measured by a plaque assay. The virus replication of rMP12-rLuc was significantly reduced in the presence of ActD (*p<0.001; Student's t-test). Data are expressed as mean +/- standard deviation of three independent experiments.