Table 2.
Hill model (1), in terms of dose di |
Hill model (2), in terms of zi = ln(di) |
|||||
---|---|---|---|---|---|---|
Parameter | MLE | S.E. | Parameter | MLE | S.E. | |
ϕ1 (min) | 0.033 | 0.010 | γ (min) | 0.033 | 0.010 | |
ϕ2 (max) | 0.673 | 0.115 | δ (max–min) | 0.641 | 0.118 | |
ϕ3 (ED50) | 55.962 | 9.392 | α (intercept) | −13.368 | 3.923 | |
ϕ4 (shape) | 3.322 | 1.084 | β (slope) | 3.322 | 1.084 |
The parameterizations are related as follows: ϕ1 = γ, ϕ2 = γ + δ, ϕ3 = exp(−α/β), ϕ4 = β.