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. 2011 Mar;9(1):96–99. doi: 10.2174/157015911795016985

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©2011 Bentham Science Publishers Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. (2) — Similar MDMA-induced (30 mg/kg, i.p.) hyperthermia was observed in male and female mice within each genotype. Body temperature areas-under-the-curve were analyzed by repeated-measures ANOVA. (A) Sex, F_1,10 = 0.181, p = 0.6796; Time, F_4,40 = 4.741, p = 0.0032; Sex × Time interaction, F_4,40 = 1.124, p = 0.3587. (B) Sex, F_1,27 = 0.134, p = 0.7170; Time, F_4,108 = 62.705, p < 0.0001; Sex × Time interaction, F_4,108 = 1.231, p = 0.3021. (C) Sex, F_1,15 = 2.350, p = 0.1461; Time, F_4,60 = 26.22, p < 0.0001; Sex × Time interaction, F_4,60 = 2.059, p = 0.0974.