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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: Sci Transl Med. 2010 Sep 15;2(49):49ra67. doi: 10.1126/scitranslmed.3001262

Table 2.

Gene Ontology analysis of the 227 VMRs revealed enrichment for the development and morphogenesis categories (P < 0.01).

P FDR Odds
ratio
Observed
count
Expected
count
GO term Genes
0.0011 0.22 7.04 5 0.79 Anterior/posterior pattern formation HOXA5, HOXB6, HOXD8, HOXC10, HOXA1
0.0019 0.22 43.31 2 0.07 Blastoderm segmentation HOXB6, HOXD8
0.0019 0.22 43.31 2 0.07 Determined anterior/posterior axis, embryo HOXB6, HOXD8
0.0082 0.25 17.31 2 0.14 Neuron recognition FOXG1, NTM
0.0086 0.25 3.63 6 1.77 Pattern specification process HOXA5, FOXG1, LEF1, HOXC10, MYF6, HOXA1
0.0096 0.25 7.47 3 0.44 Placenta development ESX1, LEF1, CDX4
0.0096 0.25 15.74 2 0.15 Intra-Golgi vesicle-mediated transport COPZ1, GABARAPL2