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HPLC chromatograms of rat serum after administration of SHXXT. (a) serum specimen before hydrolysis (b) serum specimen hydrolyzed with β-glucuronidase (c) serum specimen hydrolyzed with sulfatase/glucuronidase 1: baicalein, 2: aloe-emodin, 3: wogonin, 4: rhein, 5: emodin, 6: chrysophanol, IS: 2-methylanthraquinone.
