Table III.
Clinical outcome.
| Embryos frozen in a medium containing |
P-value | ||
|---|---|---|---|
| 0.1 M sucrose (control) | 0.3 M sucrose (intervention) | ||
| Number of couples randomized | 99 | 102 | |
| Cumulative live birthsa | 52/99 (53%) | 43/102 (42%) | 0.17b |
| Outcome of embryo transfer in fresh cycle | |||
| Number of couples having embryo transfer | 95 | 93 | |
| Number of couples with live births | 35/95 (37%) | 36/93 (39%) | 0.91 |
| Number of babies born | |||
| Singleton | 21 | 23 | |
| Twin | 13c | 13d | |
| Triplet | 1 | 0 | |
| Number of: | |||
| Clinical pregnancies | 37 | 39 | |
| Miscarriages | 2 | 1 | |
| Terminations | 0 | 1 | |
| Ectopic pregnancies | 0 | 1 | |
| Stillbirths | 1 | 1 | |
| Neonatal deaths | 1 | 0 | |
| Outcome of embryo transfer over all frozen cycles | |||
| Number of couples having ≥1 frozen embryo transfer | 63 | 59 | |
| Number of couples with at least one live birth | 19/63 (30%) | 9/59 (15%) | 0.08 |
| Number of live births per embryo transfere | 21/89 (24%) | 10/87 (11%) | |
| Number of babies born over all frozen embryo transfers | |||
| Singleton | 16 | 8 | |
| Twin | 5 | 2 | |
| Number of: | |||
| Clinical pregnancies | 30 | 17 | |
| Miscarriages | 7 | 5 | |
| Terminations | 1 | 1 | |
| Ectopic Pregnancies | 0 | 0 | |
| Stillbirths | 1 | 1 | |
| Neonatal deaths | 0 | 0 | |
aCumulative live birth per couple is the birth of one or more live babies from the fresh and all frozen embryo transfer cycles arising from a single oocyte collection.
bCox regression adjusted for female age, female parity and couple diagnosis.
cIncludes two twin deliveries with one live birth and one stillbirth or neonatal death.
dIncludes one twin delivery with one live birth and one stillbirth.
eThree couples (two control and one intervention) had live births in two frozen transfer cycles.