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. 2011 May 16;26(8):1987–1996. doi: 10.1093/humrep/der147

Table IV.

Survival of embryos after freezing and thawing.

Embryos frozen in a medium containing
0.1 M sucrose (control) 0.3 M sucrose (intervention) OR (95% CI); P
Number of embryos frozen 472 500
Total number of embryos (%) thaweda 317 (67%)b 269 (54%)c
Number of embryos (%) recovered 316 (67%) 267 (53%)
Number of embryos (%) fully intact 180/316 (57%) 196/267 (73%) 2.9 (1.6, 5.4); <0.001d
Number of embryos (%) with ≥50% of blastomeres intact 252/316 (80%) 239/267 (90%) 2.4 (1.3, 4.2); 0.003d

OR, odds ratio; CI, confidence interval.

aIncludes embryos thawed for couples intending embryo transfer and those for couples who allowed observation of their embryos before they were discarded.

bFifteen embryos frozen on Day 1, 290 on Day 2 and 12 on Day 3 post insemination.

cTwenty three embryos frozen on Day 1, 224 on Day 2 and 22 on Day 3 post insemination.

dRandom effect logistic model includes random effect for couple and treatment effect is adjusted for day of embryo freezing.