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. 2011 Jun 10;26(8):2165–2177. doi: 10.1093/humrep/der176

Table IV.

Impact of GVT into fresh Grade 1 cytoplasts on the meiotic and developmental competence of GVs artificially compacted and/or vitrified.

Treatment n GVT Fused (%) Nuclear status after in vitro maturation (%)
n Developmental competence after in vitro fertilization (%)
MII or MII/fused Normal MII spindle Cleaved/MII Morulae/cleaved Blastocysts/cleaved
None 95 78.2 ± 6.5a,c 89.2 ± 5.8a 91 77.1 ± 5.4a 29.4 ± 3.2a 35.3 ± 6.0a
92 + 75.0 ± 2.9a 56.4 ± 4.9b 82.0 ± 12.5a 92 63.6 ± 8.1b 28.6 ± 9.2a 14.3 ± 8.3b
GV compaction 91 80.4 ± 3.3c 89.0 ± 6.3a 90 73.2 ± 4.1a,b 30.0 ± 3.9a 36.7 ± 2.7a
91 + 69.7 ± 6.1a 60.6 ± 6.5b 84.2 ± 9.2a 93 68.3 ± 5.5a,b 27.8 ± 9.2a 16.7 ± 8.3b
Vitrification 95 52.7 ± 6.3b 44.0 ± 12.0b 89 31.0 ± 7.9c 0b 0c
92 + 73.5 ± 4.4a 51.5 ± 8.1b 83.3 ± 7.8a 91 58.8 ± 7.5b 10.4 ± 6.3c 14.5 ± 9.2b
GV compaction + vitrification 91 70.6 ± 5.7a 89.1 ± 8.2a 88 69.4 ± 7.6a,b 21.0 ± 9.0a,c 16.4 ± 10.2b
92 + 71.5 ± 8.5a 53.1 ± 5.2b 82.9 ± 10.8a 95 64.7 ± 7.0b 27.3 ± 5.6a 15.1 ± 9.4b

Within columns, values (mean ± SD; six replicates) with different superscripts are different (P< 0.05). MII, metaphase II.