Table 1. ROI size (mm3), and MAX (% of baseline) and TTP (seconds) of the BOLD response in left (contralesional (cl)) and right (ipsilesional (il)) sensorimotor cortical areas, following DICS in left (contralesional) M1 for groups C, S-3d, and S-28d.
| C | S-3d | S-28d | |
|---|---|---|---|
| S2 (left (cl)) | |||
| Size (mm3) | 11.6±3.4 | 10.7±2.2 | 11.0±1.6 |
| MAX (%) | 1.2±1.4 | 2.2±1.1 | 2.2±0.6 |
| TTP (seconds) | 3.3±0.7 | 4.1±0.9 | 3.8±0.4 |
| S1fl (left (cl)) | |||
| Size (mm3) | 13.1±1.4 | 12.1±2.7 | 10.7±6.4 |
| MAX (%) | 2.3±1.1 | 3.4±2.0 | 3.1±1.5 |
| TTP (seconds) | 5.0±1.5 | 6.4±2.2 | 5.9±1.5 |
| M2 (left (cl)) | |||
| Size (mm3) | 12.0±6.6 | 9.5±5.4 | 8.5±4.8 |
| MAX (%) | 3.6±2.2 | 2.3±1.1 | 4.6±2.7 |
| TTP (seconds) | 5.4±0.9 | 6.4±2.6 | 8.0±4.9 |
| M2 (right (il)) | |||
| Size (mm3) | 18.4±4.5 | 16.7±7.2 | 10.9±4.5 |
| MAX (%) | 2.0±1.8 | 2.6±1.1 | 3.7±1.1 |
| TTP (seconds) | 4.1±0.6 | 6.6±0.3a | 5.2±1.4 |
| M1 (right (il)) | |||
| Size (mm3) | 19.9±3.4 | 15.0±5.0 | 13.8±4.9 |
| MAX (%) | 1.5±1.1 | 2.3±1.4 | 2.5±1.1 |
| TTP (seconds) | 4.2±0.4 | 6.6±0.6a | 5.3±1.5 |
| S1fl (right (il)) | |||
| Size (mm3) | 13.0±3.3 | 3.2±4.5a | 8.0±3.3 |
| MAX (%) | 1.7±1.8 | 1.6±0.4 | 1.6±0.7 |
| TTP (seconds) | 3.0±0.7 | 5.1±0.7a | 4.3±1.3 |
BOLD, blood oxygenation level-dependent; DICS, direct intracortical stimulation; M1, primary motor cortex; M2, secondary motor cortex; ROI, region-of-interest; S1fl, forelimb region of the primary somatosensory cortex; S2, secondary somatosensory cortex; TTP, time-to-peak.
Regions around the cortical stimulation site (left M1) and inside the lesion territory (right, ipsilesional S2) were excluded from ROI analysis.
a
P<0.05 versus C.