| 1 |
Identification of differentially expressed genes in PE |
Transcription profiling data from decidual basalis |
Norwegian PE and non-PE women |
| 2 |
Identify genes from step no. 1 that are expressed above background level in the SAFHS blood lymphocytes |
Transcription profiling data from blood lymphocytes |
San Antonio Family Heart Study |
| 3 |
Investigate if the genes from step no. 2 are correlated with variation in lipid levels |
Transcription profiling data from blood lymphocytes |
San Antonio Family Heart Study |
| 4 |
Identify SNPs that are genotyped in the top gene from step no. 3 |
Genome-wide SNP data |
San Antonio Family Heart Study |
| 5 |
Test if the SNPs from step no. 4 are associated with variation in lipid levels |
Lipid levels and SNPs |
San Antonio Family Heart Study |
| 6 |
Test if the SNPs from step no. 4 are associated with transcription level of the gene (cis-regulation) |
Transcription profiling data (blood lymphocytes) and SNPs |
San Antonio Family Heart Study |
