Table 3. Association of the SNPs in the ACOX2 gene region with the transcription level of the gene and with triglyceride levels.
SNP name | Positions | Effective allele | Effective allele frequency | P-value cis-regulation | P-value triglycerides |
---|---|---|---|---|---|
rs6795193 | 58472819 | A | 0.22 | 0.2337 | 0.2082 |
rs4317122 | 58473883 | A | 0.32 | 0.0815 | 0.0161 |
rs4681689 | 58477748 | A | 0.19 | 0.0464 | 0.0051b |
rs7651276 | 58481890 | A | 0.17 | 0.3747 | 0.1731 |
rs1127745a | 58487277 | G | 0.14 | 0.0045b | 0.8671 |
rs13434020a | 58487940 | C | 0.14 | 0.0045b | 0.8671 |
rs4681690 | 58490606 | C | 0.2 | 0.2628 | 0.4463 |
rs4387990 | 58491423 | A | 0.37 | 0.6437 | 0.6499 |
rs1127745 and rs13434020 are in complete LD.
P-value <0.05 after Bonferroni correction for seven independent SNPs test.