Figure 1.

The expanded HDN (eHDN). In the eHDN, each node corresponds to a distinct disease and is colored based on the disease class to which it belongs. The names of the 19 disease classes are shown on the right. Links between diseases in the same disease class are correspondingly colored and links connecting different disease classes are gray. The size of each node is proportional to the number of genes associated with the corresponding disease, and the thickness of the link is proportional to the number of genes shared by the diseases it connects. Diseases with >10 associated genes are named.