Table 4.
Antioxidant/antioxidant enzyme and TBARS levels in liver homogenate and serum of swim stress-induced ulcer model.
| Groups | GSH (nmol g−1 tissue) | TBARS (nmol mg−1 protein) | SOD (U mg−1 protein) |
|---|---|---|---|
| Liver | |||
| Healthy | 236.6a ± 47.7 | 1.31a, b ±0.4 | 27.04a, b ± 3.4 |
| Swim stress induced | 157.3c ± 12.2 | 4.04d ± 1.1 | 15.78d ± 3.7 |
| Karanjin control | 215.1a ± 29.6 | 1.43a, b ± 0.3 | 26.14a, c ± 2.1 |
| Karanjin 10 mg kg−1 b.w. | 217.3a ± 20.2 | 1.86c ± 0.5 | 25.21c ± 3.2 |
| Karanjin 20 mg kg−1 b.w. | 292.3b ± 73.9 | 1.71a, c ± 0.5 | 30.38b ± 2.9 |
| Omeprazole control | 218.1a ± 18.2 | 1.16b ± 0.4 | 26.41a, c ± 3.1 |
| Omeprazole 20 mg kg−1 b.w. | 222.1a ± 16.9 | 1.53a, b ± 0.3 | 28.93a, b ± 2.7 |
| Oil treated | 110.2a ± 19.5 | 1.92c ± 0.3 | 17.00d ± 1.9 |
|
| |||
| Serum | |||
| Healthy | 10.6a, b ± 2.3 | 0.077b ± 0.04 | 2.28b ± 0.3 |
| Swim stress induced | 5.9d ± 0.8 | 0.190c ± 0.007 | 1.12d ± 0.1 |
| Karanjin control | 10.1a, b ± 1.4 | 0.065b ± 0.007 | 2.10a, b ± 0.3 |
| Karanjin 10 mg kg−1 b.w. | 8.9a, c ± 1.1 | 0.079b ± 0.001 | 1.97a, c ± 0.1 |
| Karanjin 20 mg kg−1 b.w. | 11.6b ± 1.2 | 0.073b ± 0.003 | 2.19a, b ± 0.2 |
| Omeprazole control | 8.0c ± 2.0 | 0.077b ± 0.005 | 2.35b ± 0.3 |
| Omeprazole 20 mg kg−1 b.w. | 10.5a, b ± 3.9 | 0.075b ± 0.007 | 1.81c ± 0.2 |
| Oil treated | 5.1d ± 0.1 | 0.135a ± 0.017 | 1.36d ± 0.2 |
Results are expressed as mean ± SD (n = 6). Range was provided by Duncan multiple-range test at P < .05. Different letters a–d in the column represent values that are significantly different when ulcer induced group was compared with healthy control and sample treated groups. aless significant; bless or not significant; cmoderately significant and dvery significant.