Table 3.
Details of BA and SFA flow-mediated, endothelium-dependent dilation and GTN-mediated, endothelium-independent dilation in a group of healthy subjects
| BA | SFA | P Value | |
|---|---|---|---|
| Diameter, mm | 4.5 ± 0.6 | 7.0 ± 0.7 | <0.001 |
| Peak FMD diameter, mm | 4.8 ± 0.6 | 7.5 ± 0.8 | <0.001 |
| Time to peak diameter, s | 76 ± 33 | 130 ± 71 | <0.001 |
| FMD, % | 5.6 ± 2.0 | 5.8 ± 2.4 | 0.56 |
| SRAUC*, s (103) | 15.2 ± 8.0 | 10.9 ± 6.7 | <0.001 |
| Peak GTN diameter, mm | 5.2 ± 0.6 | 7.8 ± 0.9 | <0.001 |
| GTN, % | 17.1 ± 5.3 | 9.9 ± 3.6 | <0.001 |
Values are means ± SD; n = 75 FMD and n = 53 glyceryl trinitrate (GTN) subjects. The shear rate area-under-the-curve (SRAUC) is presented, being the stimulus for arterial dilation during the FMD response.
*
Due to technical problems, we could not record the postdeflation shear rate in 5 subjects.