Table 2.
Within-groups analysis: CAMs (ICAM 1, VCAM and E-selectin).
| Visit 1 | Visit 2 | Visit 1 | Visit 2 | Visit 1 | Visit 2 | ||
|---|---|---|---|---|---|---|---|
| ICAM-1 | ICAM-1 | VCAM-1 | VCAM-1 | E-SEL | E-SEL | ||
| DP | Mean | 37.1 ± 26.1 | 33.8 ± 25.8 | 14.2 ± 10.1 | 14.0 ± 9.9 | 33.0 ± 25.3 | 28.0 ± 25.7 |
| P (two-tailed t-test) | 0.03 | 0.79 | 0.004a | ||||
| N = 19 | |||||||
| Placebo | Mean | 30.1 ± 20.6 | 27.4 ± 21.2 | 12.0 ± 8.1 | 11.5 ± 6.8 | 27.9 ± 16.2 | 24.8 ± 19.1 |
| P (two-tailed t-test) | 0.36a | 0.97a | 0.37a | ||||
| N = 20 |
E-SEL = E-selectin; aWilcoxon Signed Ranks Test; Visit 1—baseline measurements; Visit 2—measurements taken after 12 weeks of study medication.