Table 3.

Decline in eGFR by cystatin C and creatinine over 5 years among MESA participants without CKD by Hispanic ethnicity and country of origin

Ethnicity	N	Model 1 Adjusteda β (95% CI)	P	Model 2 Adjustedb β (95% CI)	P	Model 3 Adjustedc β (95% CI)	P
eGFRcys ml/min per 1.73 m2
white	1989	Ref		Ref		Ref
all Hispanics	1164	−0.29 (−0.47, −0.11)	0.002	−0.27 (−0.45, −0.09)	0.004	−0.28 (−0.46, −0.09)	0.003
Mexican/Central American	503	−0.23 (−0.48, 0.01)	0.06	−0.20 (−0.45, 0.05)	0.110	−0.22 (−0.47, 0.03)	0.08
Dominican	146	−0.55 (−0.97, −0.13)	0.01	−0.55 (−0.97, −0.13)	0.01	−0.54 (−0.97, −0.12)	0.01
Puerto Rican	153	−0.48 (−0.88, −0.07)	0.02	−0.46 (−0.87, −0.05)	0.03	−0.47 (−0.87, −0.06)	0.02
South American	94	−0.22 (−0.74, 0.31)	0.42	−0.20 (−0.72, 0.32)	0.45	−0.17 (−0.70, 0.35)	0.51
other Hispanic	268	−0.16 (−0.48, 0.16)	0.33	−0.15 (−0.47, 0.17)	0.35	−0.14 (−0.47, 0.18)	0.38
eGFR CKD EPI ml/min per 1.73 m2
white	1989	Ref		Ref		Ref
all Hispanics	1164	−0.15 (−0.28, −0.03)	0.02	−0.15 (−0.28, −0.03)	0.02	−0.14 (−0.27, −0.02)	0.03
Mexican/Central American	503	−0.11 (−0.28, 0.07)	0.23	−0.09 (−0.27, 0.08)	0.29	−0.11 (−0.28, 0.07)	0.24
Dominican	146	−0.52 (−0.81, −0.23)	<0.001	−0.54 (−0.83, −0.25)	<0.001	−0.55 (−0.84, −0.26)	<0.001
Puerto Rican	153	−0.33 (−0.61, −0.04)	0.03	−0.33 (−0.62, −0.05)	0.02	−0.33 (−0.62, −0.05)	0.02
South American	94	−0.11 (−0.47, 0.26)	0.56	−0.11 (−0.47, 0.25)	0.56	−0.02 (−0.38, 0.34)	0.91
other Hispanic	268	0.05 (−0.17, 0.27)	0.66	0.04 (−0.18, 0.26)	0.74	0.08 (−0.14, 0.31)	0.48

^aModel 1: adjusted for age, gender, income, and education.

^bModel 2: further adjusted for LDL, HDL, BMI, smoking, and CRP.

^cModel 3: further adjusted for diabetes, hypertension, and systolic blood pressure.