Table 2.
Allopurinol | Placebo | P | |
---|---|---|---|
Change in LVMI at 9 months (g/m2) | −1.42 (±4.67) | +1.28 (±4.45) | 0.036a |
Change in FMD response to hyperemia at 6 months (%) | +1.72 (±2.95) | −0.03 (±2.84) | 0.053 |
Change in FMD response to hyperemia at 9 months (%) | +1.26 (±3.06) | −1.05 (±2.84) | 0.009b |
Change in FMD response to GTN at 6 months (%) | −0.29 (±6.16) | −1.91 (±8.38) | 0.729 |
Change in FMD response to GTN at 9 months (%) | −0.50 (±5.87) | −1.06 (±6.65) | 0.918 |
Change in AIx at 6 months (%) | −0.04 (±7.19) | +3.41 (±5.37) | 0.048a |
Change in AIx at 9 months (%) | −4.70 (±9.30) | +0.77 (±6.06) | 0.015a |
Change in PWV at 6 months (m/s) | −0.06 (±1.52) | −0.56 (±1.52) | 0.141 |
Change in PWV at 9 months (m/s) | −0.39 (±1.13) | +0.20 (±1.28) | 0.086 |
GTN, glyceryl trinitrate.
aP < 0.05;
bP < 0.01.