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. 2011 Jul 15;6(7):e21877. doi: 10.1371/journal.pone.0021877

Table 1. Elevated ΔNp63α levels enhance malignant conversion in v-rasHa-expressing keratinocytes.

Normal Skin Papilloma Carcinoma Total Conversion rate
Lenti-GFP 10 0 0 10 0%
Lenti-ΔNp63α 10 0 0 10 0%
Lenti-GFP/v-rasHa 11 (73.3%) 4 (26.7%) 0 15 0%
Lenti-ΔNp63α/v-rasHa 0 0 20 (100%) 20 100%

Tumor incidence and conversion rate of grafted keratinocytes are presented at 5 weeks post-grafting. Tumor phenotypes were confirmed histologically.