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. 2011 Jul 15;6(7):e21877. doi: 10.1371/journal.pone.0021877

Table 2. Loss of p19arf cooperates with v-rasHa in malignant conversion.

Normal Skin Papilloma Carcinoma Total Conversion rate
Lenti-GFP/v-rasHa 0 5 0 5 0%
Lenti-ΔNp63α/v-rasHa 0 0 5 5 100%
p19arf null/v-rasHa 0 1 9 10 90%
p19arf null/Lenti-ΔNp63α/v-rasHa 0 0 10 10 100%

Tumor incidence and conversion rate of grafted p19arf null keratinocytes are presented at 5 weeks post-grafting. Tumor phenotypes were confirmed histologically.