Skip to main content
. 2011 Jul 15;6(7):e22223. doi: 10.1371/journal.pone.0022223

Figure 3. Epitopes for mAb 7C11 and 4C3 are located on opposite lobes of Bla g 2.

Figure 3

Ribbon diagram of rBla g 2 (gold) in complex with a Fab fragment of the mAb 4C3 (blue) superimposed to the Fab′ of mAb 7C11 in complex with Bla g 2 (allergen not shown). Monoclonal Ab 7C11 binds to the N-terminal lobe of the allergen and mAb 4C3 to the C-terminal lobe. Antibody fragments consist of a heavy and a light chain, in green and light lilac for 7C11, and in marine blue and cyan for 4C3, respectively. The carbohydrates in position N268 are shown in red.