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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: Ann Thorac Surg. 2008 May;85(5):1678–1685. doi: 10.1016/j.athoracsur.2008.01.043

Fig 2.

Fig 2

Effect of Toll-like receptor 4 (TLR4) mutation on nuclear factor (NF)-κB phosphorylation. (A) A representative gel shows results after hearts of wild-type (WT) and TLR4-defective (TLR4-def) mice underwent either 40 minutes of perfusion (C–control), 20 minutes of ischemia (I), or 20 minutes of ischemia followed by 60 minutes of reperfusion (I/R). (B) Densitometry data of two separate experiments show that levels of phosphorylated NF-κB p65 increased after ischemia and ischemia/reperfusion in WT hearts (black bars), but not in TLR4-defective hearts (white bars).