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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Pediatr. 2011 Apr 13;159(3):392–397. doi: 10.1016/j.jpeds.2011.02.035

Table 3.

Multivariate Regression Analysis of Risk Factors for NEC

Characteristic Adjusted OR (95% CI)* p-value*
SGA 3.40 (0.96, 12.05) 0.058
RDS 0.46 (0.24, 0.88) 0.018
Type of feed
 Breast milk 0.57 (0.30, 1.10) 0.093
 Breast milk & formula 0.74 (0.39, 1.41) 0.360
 No feeds 0.90 (0.28, 2.85) 0.854
 Formula Reference
Full feeds reached 2.11 (1.08, 4.10) 0.028
Sepsis 11.20 (3.44, 36.45) <0.0001
Antibiotic exposure 1.10 (1.02, 1.19) 0.015
Sepsis by Antibiotic Exposure 0.85 (0.78, 0.94) 0.001
*

Conditional Logistic Regression

Abbreviations: NEC, necrotizing enterocolitis; OR, odds ratio; CI, confidence interval; SGA, small for gestational age; RDS, respiratory distress syndrome