Table 1.
UPDRS = Unified Parkinson’s Disease Rating Scale; LEU = L-dopa equivalent units; DA = dopamine agonists. All values are mean ± SD. Significant differences are labeled with “*”. Controls, PD patients with (PD+ICB) and without (PD-ICB) impulsive compulsive behaviours.
| Controls | PD+ICB | PD-ICB | t value, χ 2 and F-value | p-value | |
|---|---|---|---|---|---|
| Participants (no.) | 24 | 27 | 25 | ||
| Age (yrs) | 57.8 ± 10.7 | 54.2 ± 9.2 | 64.2 ± 8.0 | F = 7.6 | =0.001* |
| Gender (male) | 14 | 22 | 21 | χ 2 = 5.2 | =0.073 |
| At disease onset | - | 44.1 ± 8.7 | 52.8 ± 9.5 | t = 3.2 | =0.001* |
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| |||||
| Disease duration (yrs) | - | 10.2 ± 5.5 | 11.4 ± 7.2 | t = 0.68 | =0.5 |
| Education (yrs) | 13.2 ± 2.9 | 13.4 ± 3.0 | 14.7 ± 3.5 | F = 1.5 | =0.23 |
|
| |||||
| LEU dose(mg/day) | - | 832 ± 425 | 805 ± 400 | t = 0.2 | =0.8 |
| DA (patients) | - | 14 | 16 | χ 2 = 3.7 | =0.4 |
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| |||||
| UPDRS on | - | 16.6 ± 9.4 | 14.4 ± 5.8 | t = 0.8 | =0.4 |
| UPDRS off | - | 27.3 ± 9.0 | 26.9 ± 6.7 | t = 0.19 | =0.85 |
| Improvement in UPRDS (%) | - | 39.2 | 46.4 | ||