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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Metabolism. 2011 Apr 12;60(9):1259–1270. doi: 10.1016/j.metabol.2011.01.008

Figure 3. Effects of Diet on Fatty Liver.

Figure 3

Rat liver tissue obtained at 4 months shows negative staining for fat by Oil Red O stain in starch-fed, control rats (A) whereas diffuse micro and macrovesicular fat deposits are present in sucrose-fed rats (B). QPCR analysis of whole liver tissues shows an increase in Fatty acid synthase (C) and ATP Citrate Lysate mRNA (D) in Sucrose-fed rats. Western blots confirmed an increase in Fatty Acid Synthase protein (E) and a decrease in Enoyl CoA hydratase-1 protein in sucrose-fed rats (F). Key, A and B, Oil Red Stain, 20X magnification. *, p<0.05