Figure 1. Antiproliferative activities of demethylating agents and histone deacetylase inhibitors on ovarian cancer cells.
(A) Hey or (B) SKOv3 cells were treated with indicated concentrations of demethylating agents (DAC, AZA) and HDAC inhibitors (SAHA, TSA), individually or in combinations. Cell proliferation was determined on day 5 with SRB assays. Data plotted represent optical density of SRB stained cells treated with the different agents normalized to values for untreated control cells.
