Figure 8. Treatment with a combination of DAC and SAHA reactivates the expression of ARHI and PEG3 in xenografts.

Hey xenograft tumors were treated with a combination of DAC and SAHA for 21 days. Tumors from two mice were harvested and processed for (A) RNA extraction to quantify ARHI and PEG3 RNA transcripts by real-time RT-PCR or (B) immunohistochemical staining with anti-ARHI antibody.