Table 1.

Baseline Demographic and Clinical Characteristics, Exercise Testing Results, and Randomized Treatment Assignments

Patient Characteristics	All HF Patients (N=2320)	HF with PAD (N=157)	HF no PAD (N=2163)
Age (years, median)	59	67	59
Female Sex	28%	10%	30%
United States	89%	89%	89%
Canada	8%	10%	8%
France	3%	1%	3%
Body Mass Index (kg/m2, median)	30	28	30
Ischemic Etiology of HF	51%	83%	49%
Current Angina Pectoris Class
None	84%	79%	84%
I	9%	9%	9%
II–IV	8%	12%	7%
Moderate to Severe or Severe Mitral Regurgitation	11%	12%	11%
Rest Electrocardiographic Ventricular Conduction
Normal	43%	35%	44%
Left Bundle Branch Block	17%	17%	17%
Right Bundle Branch Block	4%	6%	4%
Intraventricular Conduction Delay	13%	13%	13%
Paced	23%	29%	23%
Creatinine in mg/dL (median)	1.2	1.4	1.2
Baseline Beta Blocker Dose Using Carvedilol Equivalent (mg/day, median)	27	31	27
Baseline Loop Diuretic Dose Using Furosemide Equivalent (mg/day, median)	40	40	40
KCCQ Overall Summary Score at Baseline (median)	68	65	68
Smoking Status
Never	37%	19%	39%
Current	17%	28%	16%
Past	46%	53%	46%
Left Ventricular Ejection Fraction (%, median)	25%	25%	25%
History of Hypertension	60%	77%	59%
History of Diabetes Mellitus	32%	45%	31%
Prior Myocardial Infarction	42%	68%	40%
Prior Chronic Obstructive Pulmonary Disease	11%	30%	9%
Prior Stroke	10%	17%	10%
Baseline Exercise Testing Medians (Q1, Q3)
Exercise Duration on Cardiopulmonary Exercise Test (minutes)	9.6 (6.9, 12.0)	8.0 (5.7, 10.0)	9.8 (7.0, 12.1)
Peak Oxygen Consumption (mL/kg/min)	14.4 (11.4, 17.7)	12.5 (10.0, 15.0)	14.6 (11.6, 17.8)
6 Minute Walk Distance (meters)	370 (299, 435)	306 (235, 393)	375 (302, 438)
Randomized Treatment Assignment
Usual Care	50%	54%	50%
Exercise Training + Usual Care	50%	46%	50%