Table 2.
Summary of the histological findings of 87 patients.
Histological Characteristic of Patients by Diagnosis | CM | Other* | Aparasitemic** | p-value*** | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | ||
Parasitized Red Blood Cells | 21 | 19 | 7 | 3 | 21 | 3 | 0 | 0 | 12 | 0 | 0 | 0 | <0.0001 | |||
Sequestration | 45 | 4 | 1 | 24 | 0 | 0 | 12 | 0 | 0 | 0.5570 | ||||||
Lobular inflammation | 14 | 22 | 12 | 2 | 6 | 14 | 0 | 4 | 5 | 5 | 2 | 0 | 0.0420 | |||
Portal Inflammation | 17 | 17 | 12 | 3 | 1 | 10 | 7 | 3 | 3 | 1 | 8 | 2 | 1 | 1 | 0 | 0.5270 |
Necrosis | 45 | 4 | 1 | 19 | 4 | 1 | 9 | 2 | 1 | 0.3250 | ||||||
Microvesicular Fat | 42 | 7 | 1 | 0 | 0 | 16 | 4 | 2 | 1 | 1 | 6 | 1 | 1 | 2 | 2 | 0.0080 |
Macrovesicular Fat | 47 | 2 | 1 | 24 | 0 | 0 | 12 | 0 | 0 | 1.0000 | ||||||
Mixed Fat | 48 | 2 | 0 | 0 | 0 | 20 | 0 | 0 | 2 | 2 | 10 | 1 | 0 | 0 | 1 | 0.0340 |
Ballooning of Hepatocytes | 49 | 1 | 20 | 4 | 9 | 3 | 0.0090 | |||||||||
Kupfer Cells Prominent | 0 | 0 | 3 | 21 | 26 | 3 | 7 | 9 | 4 | 1 | 4 | 4 | 3 | 1 | 0 | <0.0001 |
Includes 4 patients with Reye’s histology
Includes 5 patients with Reye’s histology
Fisher’s Exact P-value from a full contingency table (for first three categories) and for Reye’s vs. all other patients.