Table 2.
Characteristics of the recipients and apheresis platelet products involved in paired ATRs.
| Concordant ATR | Patient Age (years) | Product Age (days) | Equivalent Units | Volume (mL) | Month of Platelet Donation | Symptoms | Antihistamine Premedication | History of Allergy/Atopy | Per Person ATR Rate to Platelets (%) | Comment |
|---|---|---|---|---|---|---|---|---|---|---|
| 1A | 39 | 3 | 7 | 300 | April | urticaria, pruritus | No | None | 2/79 (2.5%) | |
| 1B | 12 | 3 | 7 | 300 | urticaria, pruritus, rash | Yes | None | 1/41 (2.4%) | ||
| 2A | 1 | 5 | 1 | 33 | October | dyspnea, wheezing, rash | Yes | None | 1/3 (33.3%) | 2 additional recipients of aliquots, 1 of which was concentrated. Neither caused an ATR. |
| 2B* | 65 | 5 | 6 | 100 | urticaria | Yes | None | 5/157 (3.2%) | ||
| 3A | 59 | 5 | 7 | 202 | October | urticaria | No | Asthma, penicillin (rash) | 1/14 (7.1%) | 1 additional recipient of an aliquot did not have an ATR |
| 3B | 66 | 5 | 7 | 196 | pruritus | No | None | 1/1 (100%) | ||
| 4A | 52 | 5 | 6 | 234 | May | urticaria, pruritus | No | Asthma | 5/71 (7.0%) | |
| 4B | 48 | 4 | 6 | 230 | urticaria, pruritus | Yes | Asthma | 4/36 (11.1%) | ||
| 5A | 66 | 5 | 6 | 292 | May | urticaria, pruritus | Yes | None | 3/21 (13.3%) | |
| 5B* | 63 | 5 | 6 | 100 | urticaria | Yes | None | 5/80 (6.3%) | ||
| 6A | 40 | 4 | 6 | 193 | November | urticaria, pruritus | Yes | None | 3/48 (6.3%) | |
| 6B | 46 | 5 | 6 | 200 | urticaria, pruritus | No | ondansetron (itchy eyes) | 1/19 (5/3%) |
*
Concentrated platelet unit