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Effect of CAR transduction. a Detoxication gene expression in HepG2-C3 and ES-Hep transduced with lentivirus harboring CAR (FG12-CAR) or control (FG12) plasmid at D15 and 48 h later treated for 24 H with 1 μM clotrimazole. b 1-OH-midazolam production (see supplementary Fig. 5). c Gene down-regulation after CAR transduction at D20
