Figure 3.

Effect of isolated compounds from A. carambola and DE topically administered on croton oil-induced ear edema (a) and the effect of interaction between the compounds (b). Ear edema was measured at 6 h after croton oil treatment. Animals were challenged with croton oil and so treated with the compounds 1 (apigenin-6-C-β-l-fucopyranoside) and 2 (apigenin-6-C-(-2^″-O-α-l-rhamnopyranosyl)-β-l-fucopyranoside) (1.0 mg/ear) or DE (0.1 mg/ear). Each bar represents the mean ± SEM for four to five animals. The graphic symbols denote the significance levels when compared with control groups. Significantly different from controls, *P < .05, ***P < .001.