Table 1.

Physiological and echocardiographic parameters in rat hearts.

	Control	DM
		GO-0	GO-10	GO-50	GO-100
At basal level
BW (g)	189.1 ± 14.4	153.0 ± 14.1*	138.5 ± 17.5*	165.0 ± 15.0*	154.5 ± 11.5*
Blood glucose (mg dl−1)	73.8 ± 6.5	269.2 ± 59.8*	215.0 ± 42.3*	256.8 ± 44.5*	218.3 ± 49.5*
HR (beats/min)	415.7 ± 10.5	400.0 ± 22.5	397.4 ± 29.0	418.8 ± 39.1	392.4 ± 21.3
LVEDD (mm)	5.70 ± 0.54	5.29 ± 0.38	6.10 ± 0.75	5.36 ± 0.43	6.07 ± 0.62
LVESD (mm)	2.60 ± 0.29	2.61 ± 0.03	2.95 ± 0.51	2.68 ± 0.29	3.11 ± 0.28
FS (%)	49.8 ± 2.0	48.6 ± 3.5	49.3 ± 4.0	48.0 ± 2.1	49.6 ± 3.9
EF (%)	87.6 ± 0.9	86.7 ± 2.9	86.7 ± 3.5	87.4 ± 1.3	85.6 ± 3.0
CO (l min−1)	0.20 ± 0.05	0.19 ± 0.08	0.20 ± 0.06	0.19 ± 0.02	0.19 ± 0.01
LVM (mg)	13.22 ± 0.05	13.29 ± 0.01	13.55 ± 0.03	13.42 ± 0.02	13.50 ± 0.07
After 16-day feeding of different doses of garlic oil
BW (g)	331.3 ± 10.5	225.0 ± 14.4*	155.0 ± 20.2*	202.5 ± 30.3*	212.5 ± 21.7*
Blood glucose (mg dl−1)	96.0 ± 7.4	412.0 ± 12.7*	423.5 ± 7.8*	467.5 ± 19.3*	453.8 ± 18.3*
HR (beats/min)	413.5 ± 1.4	279.0 ± 10.2*	323.0 ± 1.6*	364.5 ± 26.8#	439.7 ± 13.6#
LVEDD (mm)	6.65 ± 0.2	6.93 ± 0.23	7.70 ± 0.17*	7.45 ± 0.29	7.65 ± 0.29*
LVESD (mm)	2.45 ± 0.14	4.60 ± 0.01*	4.65 ± 0.29*	4.15 ± 0.87∗,#	3.30 ± 0.58∗,#
FS (%)	62.6 ± 3.6	33.5 ± 2.3*	39.4 ± 0.8*	44.2 ± 0.9*	57.6 ± 1.3#
EF (%)	93.4 ± 1.7	68.0 ± 3.0*	75.6 ± 0.8*	80.5 ± 0.9∗,#	90.8 ± 0.8#
CO (l min−1)	0.15 ± 0.66	0.13 ± 0.38	0.25 ± 0.17	0.23 ± 0.01	0.37 ± 0.03∗,#
LVM (mg)	13.27 ± 0.17	13.21 ± 0.04	13.21 ± 0.04	13.17 ± 0.01	13.16 ± 0.06
LVM/TL (mg mm−1)	0.329 ± 0.001	0.413 ± 0.009*	0.358 ± 0.019	0.343 ± 0.013#	0.323 ± 0.002#

Results are mean ± SEM.

*P < .05 versus with control group. ^# P < .05 versus with GO-0 group (n = 6 rats in each group).