Table 3.
Patient characteristics at pre-SCPC and final study visits
| Pre-SCPC | High-risk | Low-risk | P | Final visit | High-risk | Low-risk | P |
|---|---|---|---|---|---|---|---|
| N †† | 38 | 116 | N | 37 | 110 | ||
| Weight z* | −1.9±1.0 | −1.5±1.2 | 0.07 | Weight z* | −0.7±1.1 | −0.4±1.1 | 0.28 |
| Height z* | −1.6±1.3 | −1.1±1.2 | 0.03 | Height z* | −1.3±1.1 | −0.8±1.1 | 0.02 |
| HC z* | −1.5±1.3 | −1.3±1.2 | 0.50 | HC z | −0.4±1.2 | −0.1±1.5 | 0.17 |
| Median BNP | Median BNP | ||||||
| 80 (44–155) | 71 (30–161) | 0.67 | 40 (18–109) | 29 (16–58) | 0.30 | ||
| (pg/ml) (IQR) | (pg/ml) (IQR) | ||||||
| EDVz* | 1.7±2.6 | 2.1±2.4 | 0.46 | EDVz* | 1.6±3.5 | 1.0±1.9 | 0.99 |
| ESVz* | 2.7±3.8 | 3.3±3.6 | 0.29 | ESVz* | 3.1±6.1 | 2.0±2.8 | 0.91 |
| EF% | 59±9 | 58±10 | 0.37 | EF% | 58±14 | 59±9 | 0.89 |
| Mass z* | 4.1±3.5 | 4.2±2.8 | 0.67 | Mass z* | 3.7±2.9 | 2.5±2.3 | 0.02 |
| Mass/vol | 1.33±0.55 | 1.22±0.48 | 0.30 | Mass/vol | 1.29±0.45 | 1.15±0.41 | 0.09 |
| Mass/vol z* | 2.7±3.6 | 2.0±3.1 | 0.30 | Mass/vol z* | 2.5±2.9 | 1.6±2.7 | 0.09 |
| Mod AVVR | 27% | 25% | 0.83 | ≥Mod AVVR | 14% | 17% | 0.80 |
| O2 sats (%) | 75±8 | 76±7 | 0.35 | O2 sats (%) | 84±4 | 83±10 | 0.55 |
| ††EDP | 8±3 | 8±4 | 0.94 | ||||
| (mmHg) | |||||||
| Stroke vol | 13±5 | 14±6 | 0.37 | Stroke vol | 17±8 | 17±5 | 0.87 |
| HR (bpm) | 118±18 | 123±19 | 0.26 | HR (bpm) | 112±14 | 114±14 | 0.61 |
| SBP (mmHg) | 88±11 | 88±14 | 0.43 | SBP (mmHg) | 89±15 | 90±17 | 0.95 |
| SBPz | 0.29±1.11 | 0.23±1.37 | 0.79 | SBPz | −0.13±1.48 | −0.08±1.64 | 0.87 |
| DBP (mmHg) | 43±13 | 46±12 | 0.08 | DBP (mmHg) | 48±15 | 49±13 | 0.70 |
| DBPz | −0.11±1.4 | 0.18±1.29 | 0.24 | DBPz | 0.24±1.62 | 0.33±1.47 | 0.77 |
| Ross HF | Ross HF | ||||||
| 0.26 | 0.39 | ||||||
| score | score | ||||||
| I | 68% | 50% | I | 76% | 82% | ||
| II | 13% | 28% | II | 11% | 9% | ||
| III | 13% | 21% | III | 13% | 9% | ||
| IV | 6% | 1% | IV | 0% | 0% |
z score differs from zero, p<0.05
At the pre-SCPC visit, sample size varies from 30–38 for the high-risk and 107–116 for the low-risk group. At the final study visit, sample size ranges from 33–37 in the high-risk and 105–110 in the low-risk group, with the exception of BNP, which had group sizes of 27 and 85, respectively.
SCPC = superior cavopulmonary connection; HC = head circumference; BNP = B-type natriuretic peptide; EDV = end-diastolic volume; ESV = end-systolic volume; Mod AVVR = moderate atrio-ventricular valve regurgitation; EF = ejection fraction; O2 sats = Oxygen saturation;
EDP = end-diastolic pressure (only available at pre-SCPC cardiac catheterization); HR = Heart rate; bpm = beats per minute; SBP = systolic blood pressure; DBP = diastolic blood pressure; HF = Heart failure; IQR=interquartile range