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. 2011 Jul 17;343:d4065. doi: 10.1136/bmj.d4065

Table 5.

 Comparison of mobilisation-observation-behaviour-intensity-dementia-2 (MOBID-2) pain scale total score between control and intervention (stepwise protocol for treatment of pain) groups using repeated measures analysis of covariance (ANCOVA)*

Week Mean (SD) MOBID-2 total Effect of intervention on MOBID-2 total† Intracluster correlation coefficient‡
Control group Intervention group Estimate (95% CI) P value
0 3.7 (2.5), n=163 3.8 (2.7), n=164 0.094
2 3.5 (2.4), n=159 2.9 (2.5), n=152 −0.7 (−0.4 to −1.1) <0.001 0.070
4 3.3 (2.4), n=155 2.7 (2.2), n=146 −0.8 (−0.4 to −1.2) <0.001 0.059
8 3.5 (2.6), n=154 2.3 (2.1), n=145 −1.3 (−0.8 to −1.7) <0.001 0.082
12 3.5 (2.5), n=151 2.9 (2.6), n=140 −0.8 (−0.3 to −1.2) 0.001 0.139

*Baseline score as covariate and least squares weighted by number of patients within cluster; P value from multivariate test of intervention was <0.001, and cross effect between week and intervention was 0.009.

†Variable estimate by week of effect of intervention on MOBID-2 from estimated model.

‡Proportion of total variance between clusters, and measured within framework of ANCOVA.