FIGURE 1.
Infection with Salmonella causes marked splenomegaly. C57BL/6 mice were infected intravenously with 5 ×105 attenuated Salmonella, BRD509. Groups of infected mice were sacrificed every week, and spleen weight and bacterial loads were determined. A, Graph shows the mean spleen weight ± SD of Salmonella-infected mice from three to four mice per time points and is representative of two separate experiments. B, Graph shows mean bacterial CFUs ± SD from three to four mice per group and is representative of two separate experiments.