Table 2.
Metabolites and Methylation index | Total subjects (n = 57) GM (95% CI) | Subjects without skin lesions (n = 21) GM (95% CI) | Subjects with skin lesion (n = 36) GM (95% CI) |
---|---|---|---|
TAs (μg/g Cr) | 31.97 (34.35–47.54) | 26.0 (18.68–63.9) | 36.09 ** (35.1–49.82) |
iAsIII (μg/g Cr) | 2.97 (3.33–5.05) | 2.33 (1.83–2.97) | 3.41 ** (2.7–4.3) |
MMAV(μg/g Cr) | 4.69 (3.99–5.51) | 3.47 (2.78–4.35) | 5.59 *** (4.55–6.85) |
DMAV (μg/g Cr) | 23.41 (23.49–32.57) | 19.67 (15.29–25.29) | 25.91 * (21.29–31.54) |
iAsV (μg/g Cr) | 0.9 (0.71–1.14) | 0.57 (0.40–0.79) | 1.18 *** (0.88–1.59) |
Percent iAsIII (%) | 9.17 (8.31–10.12) | 8.98 (8–10.08) | 9.28 (8.02–10.73) |
Percent MMAV (%) | 14.50 (13.4–15.67) | 13.36 (11.53–15.49) | 15.21 (13.87–16.65) |
Percent DMAV (%) | 72.38 (70.57–74.24) | 75.65 (73.49–77.87) | 70.54 *** (68.15–73.03) |
Percent iAsV (%) | 2.78 (2.34–3.31) | 2.18 (1.72–2.76) | 3.21 ** (2.54–4.06) |
PMI | 1.32 (1.14–1.53) | 1.37 (1.11–1.69) | 1.29 (1.05–1.59) |
SMI | 4.99 (4.54–5.49) | 5.66 (4.77–6.72) | 4.64 ** (4.15–5.18) |
Abbreviations: CI, confidence interval; Cr, creatinine; GM, geometric mean.
The difference is significant at p < 0.01 compared with subjects without skin lesions;
The difference is significant at 0.01 < p < 0.05 compared with subjects without skin lesions;
The difference is significant at 0.05 < p < 0.1 compared with subjects without skin lesion.