Table 4.
Association of inflammatory genotypes with long-term functional outcome of an IS.
| Genotypes | Logistic regression | ||||
| TNF-α-308G>A | Presence of GG | ||||
|---|---|---|---|---|---|
| 6-month outcome | AG | GG | OR* | 95% CI | P |
| (BI: 16–20) good (%) (BI: <16, or death) bad (%) |
15 (17) 13 (25.5) |
73 (83) 38 (74.5) |
Referent 0.19 |
0.04–0.86 | .03 |
| IL6-174G>C | Presence of GC/CC | ||||
| GG | GC/CC | OR* | 95% CI | P | |
| (BI: 16–20) good (%) (BI: <16, or death) bad (%) |
54 (64.3) 34 (62.8) |
30 (35.7) 21 (38.2) |
Referent 1.14 |
0.37–3.54 | .82 |
| IL12B 1188A>C | Presence of AC | ||||
| AA/CC | AC | OR* | 95% CI | P | |
| (BI: 16–20) good (%) (BI: <16, or death) bad (%) |
48 (54.5) 37 (72.5) |
40 (45.5) 14 (27.5) |
Referent 0.69 |
0.23–2.09 | .52 |
| IL4-589C>T | Presence of CT | ||||
| CC | CT | OR* | 95% CI | P | |
| (BI: 16–20) good (%) (BI: <16, or death) bad (%) |
71 (84.1) 43 (84.3) |
14 (15.9) 8 (15.7) |
Referent 0.67 |
0.17–2.59 | .56 |
| IL10-1082G>A | Presence of GG | ||||
| GG | AG/AA | OR* | 95% CI | P | |
| (BI: 16–20) good (%) (BI: <16, or death) bad (%) |
14 (15.9) 12 (23.5) |
74 (84.1) 39 (76.5) |
Referent 2.65 |
0.57–12.40 | .22 |
BI: barthel index, OR: odds ratio, CI: confidence intervals.
*ORs adjusted for age, sex, hypertension, diabetes, hyperlipidemia, ischemic heart disease, smoking, stroke severity on admission and TOAST categories.