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. 2011 Jul 13;31(28):10311–10322. doi: 10.1523/JNEUROSCI.0915-11.2011

Table 3.

Effects of intra-Str injections of muscimol and methyl l-DOPA on response parameters of MC-responsive GPe neurons

Muscimol (N = 6)
Methyl-l-DOPA (N = 6)
Before After Before After
Average firing rate 28.3 ± 5.8 p < 0.02 42.4 ± 9.7 28.7 ± 8.6 P < 0.05 40.6 ± 13.6
Burst index, % 38.9 ± 13.5 p < 0.001 17.1 ± 2.2 43.0 ± 8.2 P < 0.005 25.9 ± 11.0
Early excitation, n 6 6 6 1
    Latency (ms) 7.3 ± 1.0 ns 8.0 ± 1.7 7.3 ± 1.5 —- 8.2
    Duration (ms) 3.7 ± 0.8 ns 4.2 ± 0.9 3.5 ± 0.8 —- 5.2
    Strength (spikes) 14.6 ± 3.7 ns 21.5 ± 11.2 12.1 ± 2.6 —- 15.2
Short inhibition 6 0 6 6
    Latency 15.0 ± 2.3 14.7 ± 1.5 ns 16.2 ± 2.0
    Duration 11.0 ± 4.6 14.2 ± 2.0 P < 0.005 10.0 ± 1.1
    Strength 31.2 ± 8.4 40.3 ± 13.7 ns 38.1 ± 12.8
Late excitation 6 6 6 6
    Latency 34.0 ± 4.3 ns 31.2 ± 8.4 34.2 ± 5.2 ns 38.7 ± 10.8
    Duration 80.0 ± 33.6 p < 0.005 23.8 ± 8.9 153.2 ± 45.4 P < 0.02 66.2 ± 38.3
    Strength 214.9 ± 102.7 p < 0.02 100.5 ± 54.1 457.2 ± 189.8 P < 0.02 222.2 ± 116.2

Statistics: Paired t test. ns, Not significant; —-, not compared.