TABLE 2. Cardiac Catheterization Data.

Patient	Age (yrs)	Status	PAP (mm Hg)	AOP (mm Hg)	CI (l/min/m2)	PVRI (U · m2)	PVR/SVR
1	4.9	Baseline	70	74	4.2	15.0	0.95
	6.3	EPO	56	73	4.3	11.3	0.69
	6.6	EPO + BOS	27	68	4.5	4.3	0.29
2	0.1	Baseline	55	55	2.5	22.0	1.00
	6.6	EPO	25	64	4.9	3.1	0.27
	8.2	BOS	24	62	2.6	5.6	0.24
3	0.4	Baseline	67	60	2.2	27.3	1.20
	6.7	EPO	39	80	4.5	6.6	0.40
	7.0	EPO + BOS	35	69	4.6	6.5	0.46
4	0.1	Baseline	63	59	2.1	28.6	1.50
	4.7	EPO	55	68	5.3	7.0	0.75
	10.2	EPO + BOS	31	71	3.4	7.1	0.40
5	5.5	Baseline	65	68	3.2	17.0	0.90
	11.9	EPO	25	70	4.3	4.9	0.31
	14.5	BOS	30	84	3.1	7.2	0.28
	15.5	BOS	30	80	3.8	6.0	0.34
6	5.4	Baseline	98	75	2.6	32.0	1.39
	14.5	EPO	24	78	4.1	3.4	0.20
	15.3	BOS	24	78	4.9	3.5	0.23
7	9.1	Baseline	75	102	5.0	13.2	0.68
	14.2	EPO	66	84	6.0	9.9	0.75
	14.4	EPO + BOS	58	79	6.4	8.0	0.66
8	10.3	Baseline	120	85	2.9	46.0	1.30
	15.1	EPO	103	84	3.8	23.4	1.18
	16.2	EPO + BOS	115	70	5.5	19.5	0.79
		Baseline	77 ± 22	73 ± 16	3.1 ± 1.0	25.1 ± 10.8	1.1 ± 0.3
		EPO	49 ± 27*	74 ± 7	4.5 ± 0.5*	8.6 ± 7.2*	0.5 ± 0.4*
		BOS ± EPO	43 ± 33	72 ±7	4.1 ±1.1	7.7 ± 5.4	0.4 ± 0.2

^*p <0.05 baseline versus EPO.

AOP = mean arterial pressure; BOS = bosentan; CI = cardiac index; PAP = mean pulmonary artery pressure; PVRI = pulmonary vascular resistance index; SVR = systemic vascular resistance; other abbreviation in Table 1.