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. 2011 May 31;286(29):26127–26137. doi: 10.1074/jbc.M111.237297

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — The growth of melanoma in mice is retarded by NCAM silencing. siCTRL and siNCAM cells were transplanted subcutaneously into the back of C57BL/6J mice respectively. A, representative mice were injected with siCTRL and siNCAM cells 3 weeks post-transplantation. Arrows indicate the subcutaneous melanoma. B, specimen of melanoma tumors is shown. C, quantitative analysis of the weight of melanoma tumors is shown. *, p < 0.05; n = 6. D, expression of NCAM in tumors determined by immunohistochemistry is shown. Scale bars: 25 μm; Hematoxylin and eosin staining scale bars, 50 μm.