TABLE 1.

Plasma and CSF levels of oxysterols and cholesterol in SPG5 patients

Patient	Controls	Case 1	Case 2	Case 3
Plasma 27-OH (ng/ml)	89–243	1213	1316	1046
Csf 27-OH (ng/ml)	0.5–0.8	14	14	24
Plasma 24S-OH (ng/ml)	30–127	52	62	66
Csf 24S-OH (ng/ml)	0.8–2.4	<0.5	<0.5	1
Plasma cholesterol (mmol/liter)	3.5–8	4.3	4.5	4.1