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. Author manuscript; available in PMC: 2011 Jul 18.
Published in final edited form as: Lancet. 2010 Jul 15;376(9739):449–457. doi: 10.1016/S0140-6736(10)60666-6

Table 3.

Adjusted hazard ratios for death used in the two prognostic models: CD4 model and total lymphocyte count/haemoglobin (TLC/Hb) model.

CD4 model TLC/Hb model
Age ≥ 40 years (v. < 40 years)
 <40 (reference) 1 1
 ≥40 1.43 (1.23–1.66) 1.36 (1.12–1.64)
Sex
 Male (reference) 1 1
 Female 0.68 (0.58–0.79) 0.60 (0.50–0.73)
Clinical stage*
 Less advanced (reference) 1 1
 Advanced 2.72 (1.87–3.95) 2.96 (1.83–4.78)
CD4 count (cells/μL)
 <25 (reference) 1
 25–49 0.76 (0.62–0.94)
 50–99 0.46 (0.38–0.57)
 100–199 0.35 (0.28–0.42)
 ≥200 0.29 (0.22–0.38)
Weight (kg)
 <45 (reference) 1 1
 45–49 0.59 (0.48–0.72) 0.61 (0.47–0.79)
 50–59 0.40 (0.33–0.48) 0.40 (0.32–0.51)
 ≥60 0.24 (0.19–0.30) 0.25 (0.19–0.33)
Total lymphocyte count (cells/μL)
 0–799 (reference) 1
 800–1199 0.71 (0.55–0.91)
 ≥1200 0.53 (0.43–0.65)
Categories of anaemia
 Severe (reference) 1
 Moderate 0.71 (0.56–0.91)
 Mild or none 0.47 (0.37–0.61)

Results from Weibull models adjusted for all variables shown, based on 10,331 patients remaining in care, with missing values imputed.

*

Less advanced=WHO stage I or II, advanced=WHO stage III or IV

Severe=haemoglobin <8 g/dL, moderate=haemoglobin 8–10 g/dL in females and 8–11 g/dL in males, mild=haemoglobin 10–12 g/dL in females and 11–13 g/dL in males; none=haemoglobin >12 g/dL in females and >13 g/dL in males