Table 1.
Commercially Available Dosage Forms of Protease Inhibitors
| Agent (Brand Name) | Dosage Form | Can Be Crushed | Can Be Dispersed in Liquid |
|---|---|---|---|
| Atazanavir sulfate (ATV, Reyataz) | 100-, 150-, 200-, 300-mg capsule | No | No |
| Darunavir (DRV, Prezista) | 75-, 150-, 400-, 600-mg tablet | No | No |
| Fosamprenavir calcium (FPV, Lexiva); succeeded Amprenavir (Agenerase) | 700-mg tablet 50-mg/mL oral suspension |
No | N/A: oral suspension available |
| Indinavir (IDV, Crixivan) | 100-, 200-, 400-mg capsule | No | N/A |
| Lopinavir/ritonavir (LPV/RTV, Kaletra) | 100/25-, 200/50-mg tablet 80/20 mg/mL oral solution |
No | N/A: oral solution available |
| Nelfinavir mesylate (NFV, Viracept) | 250-, 625-mg tablet 50 mg/g oral powder |
Yes | Tablet may be dissolved in small amount of water; oral powder may be mixed with water, milk, formula, soy formula, soy milk, dietary supplements, or dairy foods |
| Ritonavir (RTV, Norvir) | 100-mg capsule 100-mg tablet 80-mg/mL oral solution |
No | Oral solution may be mixed with chocolate milk, Ensure, or Advera |
| Saquinavir mesylate (SQV, Invirase); Fortovase discontinued | 200-mg capsule 500-mg tablet |
No | No |
| Tipranavir (TPV, Aptivus) | 250-mg capsule 100-mg/mL oral solution |
No | N/A: oral solution available |