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. 2010 Jun 14;239(7):2005–2013. doi: 10.1002/dvdy.22343

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Fig. 3 — Hypoplastic AV cushions in Sur-8^Δ/flox;Tie2-Cre embryonic heart. H&E-stained histological sections of the middle portion of the atrioventricular canal showing the underdeveloped cushions in E11.5 Sur-8^Δ/flox;Tie2-Cre embryos (B) compared to that in controls (A). Scale bar = 100 μm. C: Stereologic analysis showing smaller cushion volume of Sur-8^Δ/flox;Tie2-Cre embryos compared with that of the controls. Data shown as mean ± SEM. *P < 0.05, by 2-tailed Student's t-test. cko, Sur-8^Δ/flox;Tie2-Cre; ctr, Sur-8^Δ/flox.